PD-1 anticorps

N° du produit ABIN492542

L’anticorps Souris Monoclonal anti-PD-1 a été validé pour WB, IHC (p) et EIA. Il convient pour détecter PD-1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PD-1 anticorps (ABIN492542)

Antigène: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PD-1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Clone: 12A7D7

Détail du produit anti-PD-1 anticorps

Specificité: This antibody detects CD279 / PD1.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Attributs du produit: Synonyms: Protein PD-1, hPD-1, PDCD1, Programmed cell death protein 1

Purification: Affinity chromatography

Immunogène: ~150 amino acid recombinant protein of mouse PD-1Remarks: GenBank accession no. NP_032824

Isotype: IgG

Information d'application

Indications d'application: Western blot at 1 - 2 μg/mL. A-20 cell lysate can be used as positive control. ELISA. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2 - 8 °C.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur PD-1

Antigène: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Autre désignation: CD279 / PD1

Sujet: Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antig en-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2. Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of Synonyms: PDCD1, Programmed cell death protein 1, Protein PD-1, hPD-1

ID gène: 18566

UniProt: Q02242

Pathways: Cancer Immune Checkpoints